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Detroit Lions vs Buffalo Bills Thursday Night Football preview and betting odds for Week 2

Thursday, September 17, 2026

The Buffalo Bills host the Detroit Lions on Thursday Night Football in Week 2. Both teams won their Week 1 games.

Original reporting: https://www.foxnews.com/outkick/detroit-lions-vs-buffalo-bills-thursday-night-football-preview-betting-odds-week-2

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